› how-to-disable-defenderHow to Disable Defender Antivirus & Firewall in Windows 10 ... Then open the DisableAntiVirus REG_DWORD value and change the Value data from 0 to 1 disable Windows Defender Antivirus protection. Click OK when done. 12. Proceed to the the next step to disable Windows Defender Services. Step 3. Disable Defender Security Center, Antivirus & Firewall Services.